Cannabis-induced attenuated psychotic symptoms: Implications for prognosis in young people at ultra-high risk for psychosis

MJ McHugh; PD McGorry; AR Yung; A Lin; SJ Wood; JA Hartmann; B Nelson

Journal article

Cannabis-induced attenuated psychotic symptoms: Implications for prognosis in young people at ultra-high risk for psychosis

MJ McHugh, PD McGorry, AR Yung, A Lin, SJ Wood, JA Hartmann, B Nelson

Psychological Medicine | CAMBRIDGE UNIV PRESS | Published : 2017

DOI: 10.1017/S0033291716002671

Abstract

Background Cannabis use shows a robust dose-dependent relationship with psychosis risk among the general population. Despite this, it has been difficult to link cannabis use with risk for transitioning to a psychotic disorder among individuals at ultra-high risk (UHR) for psychosis. The present study examined UHR transition risk as a function of cannabis use characteristics which vary substantially between individuals including age of first use, cannabis abuse severity and a history of cannabis-induced attenuated psychotic symptoms (APS). Method Participants were 190 UHR individuals (76 males) recruited at entry to treatment between 2000 and 2006. They completed a comprehensive baseline asse..

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University of Melbourne Researchers

Patrick McGorry Author

Stephen Wood Author

Barnaby Nelson Author

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Grants

Awarded by National Health and Medical Research Council (NHMRC) Program

Awarded by NHMRC

Awarded by National Health and Medical Research Council of Australia

Funding Acknowledgements

This work was supported by the Colonial Foundation Philanthropic Trust and by National Health and Medical Research Council (NHMRC) Program grants (no. 566529 and no. 350241). A. L. is funded by an NHMRC Early Career Fellowship (no. 1072593).